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1

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

Nakagawa, Masato, Koyanagi, Michiyo, Tanabe, Koji, Takahashi, Kazutoshi, Ichisaka, Tomoko, Aoi, Takashi, Okita, Keisuke, Mochiduki, Yuji, Takizawa, Nanako, Yamanaka, Shinya

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 1.05 MB

english, 2007

2

Induction of pluripotent stem cells from fibroblast cultures

Takahashi, Kazutoshi, Okita, Keisuke, Nakagawa, Masato, Yamanaka, Shinya

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 433 KB

english, 2007

3

Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

Yoshinori Yoshida, Kazutoshi Takahashi, Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka

Journal:

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

4

Generation of germline-competent induced pluripotent stem cells

Okita, Keisuke, Ichisaka, Tomoko, Yamanaka, Shinya

Journal:

Year:

2007

Language:

english

File:

PDF, 2.03 MB

english, 2007

5

The effect of introduction of universal childhood hepatitis B immunization in South Africa on the prevalence of serologically negative hepatitis B virus infection and the selection of immune escape variants

Keisuke Hino, Yoshiharu Katoh, Eftyhia Vardas, John Sim, Kiwamu Okita, William F. Carman

Journal:

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

6

Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development

Karagiannis, Peter, Takahashi, Kazutoshi, Saito, Megumu, Yoshida, Yoshinori, Okita, Keisuke, Watanabe, Akira, Inoue, Haruhisa, Yamashita, Jun K., Todani, Masaya, Nakagawa, Masato, Osawa, Mitsujiro, Ya

Journal:

Physiological Reviews

Year:

2019

Language:

english

File:

PDF, 4.53 MB

english, 2019

7

A more efficient method to generate integration-free human iPS cells

Okita, Keisuke, Matsumura, Yasuko, Sato, Yoshiko, Okada, Aki, Morizane, Asuka, Okamoto, Satoshi, Hong, Hyenjong, Nakagawa, Masato, Tanabe, Koji, Tezuka, Ken-ichi

Journal:

Year:

2011

Language:

english

File:

PDF, 905 KB

english, 2011

8

Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Hashizume, Osamu, Ohnishi, Sakiko, Mito, Takayuki, Shimizu, Akinori, Iashikawa, Kaori, Nakada, Kazuto, Soda, Manabu, Mano, Hiroyuki, Togayachi, Sumie, Miyoshi, Hiroyuki, Okita, Keisuke, Hayashi, Jun-I

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

9

Case of generalized pustular psoriasis that might have progressed from terbinafine-induced acute generalized exanthematous pustulosis

Yasuno, Shuichiro, Yamaguchi, Michiya, Tanaka, Akemi, Umehara, Kaori, Okita, Tomoko, Asano, Nobuyuki, Kashiwagi, Keisuke, Shimomura, Yutaka

Journal:

The Journal of Dermatology

Year:

2018

Language:

english

File:

PDF, 418 KB

english, 2018

10

Gingival Fibroblasts as a Promising Source of Induced Pluripotent Stem Cells

Egusa, Hiroshi, Okita, Keisuke, Kayashima, Hiroki, Yu, Guannan, Fukuyasu, Sho, Saeki, Makio, Matsumoto, Takuya, Yamanaka, Shinya, Yatani, Hirofumi, Klymkowsky, Mike

Journal:

Year:

2010

Language:

english

File:

PDF, 4.03 MB

english, 2010

11

Optimizing antiemetic treatment for chemotherapy-induced nausea and vomiting in Japan: Update summary of the 2015 Â Japan Society of Clinical Oncology Clinical Practice Guidelines for Antiemesis

Aogi, Kenjiro, Takeuchi, Hideki, Saeki, Toshiaki, Aiba, Keisuke, Tamura, Kazuo, Iino, Keiko, Imamura, Chiyo K., Okita, Kenji, Kagami, Yoshikazu, Tanaka, Ryuhei, Nakagawa, Kazuhiko, Fujii, Hirofumi, Bo

Journal:

International Journal of Clinical Oncology

Year:

2020

File:

PDF, 884 KB

2020

12

Differences in hypervariable region 1 quasispecies of hepatitis C virus in human serum, peripheral blood mononuclear cells, and liver

Michiari Okuda, Keisuke Hino, Masaaki Korenaga, Yuhki Yamaguchi, Yoshiharu Katoh, Kiwamu Okita

Journal:

Year:

1999

Language:

english

File:

PDF, 151 KB

english, 1999

13

Orderly hematopoietic development of induced pluripotent stem cells via Flk-1+ hemoangiogenic progenitors

Akira Niwa, Katsutsugu Umeda, Hsi Chang, Megumu Saito, Keisuke Okita, Kazutoshi Takahashi, Masato Nakagawa, Shinya Yamanaka, Tatsutoshi Nakahata, Toshio Heike

Journal:

Journal of Cellular Physiology

Year:

2009

Language:

english

File:

PDF, 723 KB

english, 2009

14

Cytokine-dependent anti-viral role of CD4-positive T cells in therapeutic vaccination against chronic hepatitis B viral infection

Fenyu Ren, Keisuke Hino, Yuhki Yamaguchi, Kiyomi Funatsuki, Akio Hayashi, Hiroaki Ishiko, Muneko Furutani, Takahiro Yamasaki, Keiko Korenaga, Satoyoshi Yamashita, Tomomi Konishi, Kiwamu Okita

Journal:

Journal of Medical Virology

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

15

Distinct geographic distributions of hepatitis B virus genotypes in patients with acute infection in Japan

Hiroshi Yotsuyanagi, Chiaki Okuse, Kiyomi Yasuda, Etsuro Orito, Shuhei Nishiguchi, Joji Toyoda, Eiichi Tomita, Keisuke Hino, Kiwamu Okita, Shiro Murashima, Michio Sata, Hiromi Hoshino, Yuzo Miyakawa,

Journal:

Journal of Medical Virology

Year:

2005

Language:

english

File:

PDF, 108 KB

english, 2005

16

A structural study of silicon-based interpenetrating polymer networks by solid state 1H and 13C NMR spectroscopy

Masatoshi Kobayashi, Shigeki Kuroki, Isao Ando, Kazuo Yamauchi, Hideaki Kimura, Koichi Okita, Manabu Tsumura, Keisuke Sogabe

Journal:

Journal of Molecular Structure

Year:

2002

Language:

english

File:

PDF, 354 KB

english, 2002

17

Permeation of methanol vapor through silica membranes prepared by the CVD method with the aid of evacuation

Koji Kuraoka, Zhang Shugen, Keisuke Okita, Taigen Kakitani, Tetsuo Yazawa

Journal:

Journal of Membrane Science

Year:

1999

Language:

english

File:

PDF, 457 KB

english, 1999

18

Hepatic expression of type I interferon receptor for predicting response to interferon therapy in chronic hepatitis C patients: a comparison of immunohistochemical method vs. competitive polymerase chain reaction assay

Daisuke Fujiwara, Keisuke Hino, Yuhki Yamaguchi, Fenyu Ren, Yasuhiro Satoh, Masaaki Korenaga, Michiari Okuda, Kiwamu Okita

Journal:

Hepatology Research

Year:

2003

Language:

english

File:

PDF, 491 KB

english, 2003

19

Hepatitis C virus infection upregulates expression of the type I interferon receptor in human peripheral blood mononuclear cells

Fenyu Ren, Keisuke Hino, Yuhki Yamaguchi, Muneko Okazaki, Akira Kitase, Yasuhiro Satoh, Masaaki Korenaga, Michiari Okuda, Kiwamu Okita

Journal:

Hepatology Research

Year:

2003

Language:

english

File:

PDF, 331 KB

english, 2003

20

Detection of hepatitis B virus DNA in liver by polymerase chain reaction for the diagnosis of fulminant hepatitis B

Chieko Suzuki, Satoyoshi Yamashita, Masaaki Korenaga, Kohichi Uchida, Kohji Tanigawa, Teruaki Kimura, Kohzoh Kayano, Masaaki Masuhara, Isao Sakaida, Keisuke Hino, Kiwamu Okita

Journal:

Hepatology Research

Year:

1998

Language:

english

File:

PDF, 71 KB

english, 1998

21

Clinical evaluation of chronic liver diseases induced by different hepatitis C virus genotype in Japan, focused on the difference between genotypes III/2a and IV/2b

Keisuke Hino, Michiari Okuda, Masaaki Korenaga, Chisa Murakami, Muneko Okazaki, Kaori Fujii, Kiwamu Okita, Fumio Tsuda, Hiroaki Okamoto, Makoto Mayumi

Journal:

Hepatology Research

Year:

1999

Language:

english

File:

PDF, 86 KB

english, 1999

22

Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues

Naoki Kimura, Makiko Takizawa, Keisuke Okita, Osamu Natori, Katsuhide Igarashi, Masaya Ueno, Kin-ichi Nakashima, Ikuo Nobuhisa, Tetsuya Taga

Journal:

Year:

2002

Language:

english

File:

PDF, 4.03 MB

english, 2002

23

Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells

Satoru Senju, Miwa Haruta, Yusuke Matsunaga, Satoshi Fukushima, Tokunori Ikeda, Kazutoshi Takahashi, Keisuke Okita, Shinya Yamanaka, Yasuharu Nishimura

Journal:

Year:

2009

Language:

english

File:

PDF, 495 KB

english, 2009

24

“Rebound” phenomenon of hepatitis C viremia after interferon therapy in “relapsed” patients with chronic hepatitis C

Hiroshi Hanada, Keisuke Hino, Kaori Fujii, Muneko Okazaki, Kiwamu Okita

Journal:

Journal of Gastroenterology

Year:

1995

Language:

english

File:

PDF, 407 KB

english, 1995

25

Cytochrome c is a possible new marker for fulminant hepatitis in humans

Isao Sakaida, Teruaki Kimura, Takahiro Yamasaki, Yohei Fukumoto, Keisuke Watanabe, Muneo Aoyama, Kiwamu Okita

Journal:

Journal of Gastroenterology

Year:

2005

Language:

english

File:

PDF, 343 KB

english, 2005

26

In situ detection of oxidized n-3 polyunsaturated fatty acids in chronic hepatitis C: correlation with hepatic steatosis

Akira Kitase, Keisuke Hino, Takakazu Furutani, Michiari Okuda, Toshikazu Gondo, Isao Hidaka, Yuichi Hara, Yuhki Yamaguchi, Kiwamu Okita

Journal:

Journal of Gastroenterology

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

27

Hepatitis C virus core protein inhibits deoxycholic acid-mediated apoptosis despite generating mitochondrial reactive oxygen species

Yuichi Hara, Keisuke Hino, Michiari Okuda, Takakazu Furutani, Isao Hidaka, Yuhki Yamaguchi, Masaaki Korenaga, Kui Li, Steven A. Weinman, Stanley M. Lemon, Kiwamu Okita

Journal:

Journal of Gastroenterology

Year:

2006

Language:

english

File:

PDF, 383 KB

english, 2006

28

Patch annulo-aortoplasty in an adult patient with congenital supravalvular aortic stenosis and a small aortic annulus

Naoto Morimoto, Keisuke Morimoto, Yoshihisa Morimoto, Akiko Tanaka, Toshihito Sakamoto, Kenji Okada, Yutaka Okita

Journal:

General Thoracic and Cardiovascular Surgery

Year:

2011

Language:

english

File:

PDF, 292 KB

english, 2011

29

Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development

Keisuke Okita, Hiroshi Kiyonari, Ikuo Nobuhisa, Naoki Kimura, Shinichi Aizawa, Tetsuya Taga

Journal:

Year:

2004

Language:

english

File:

PDF, 226 KB

english, 2004

30

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

Noriko Tsubooka, Tomoko Ichisaka, Keisuke Okita, Kazutoshi Takahashi, Masato Nakagawa, Shinya Yamanaka

Journal:

Year:

2009

Language:

english

File:

PDF, 843 KB

english, 2009

31

Molecular epidemiologic analysis of hepatitis C virus infection in injecting drug users with acute hepatitis C in Japan

YASUHIRO SATOH, KEISUKE HINO, TAKANOBU KATO, MASASHI MIZOKAMI, SATOYOSHI YAMASHITA, HIROKI NAKAMURA, KIWAMU OKITA

Journal:

Journal of Gastroenterology and Hepatology

Year:

2004

Language:

english

File:

PDF, 127 KB

english, 2004

32

417–2α-Tocopherol and ascorbic acid attenuates the ribavirin-induced decrease of eicosapentaenoic acid in erythrocyte membrane in chronic hepatitis C patients

Keisuke Hino, Yasuko Murakami, Ayako Nagai, Akira Kitase, Yuichi Hara, Takakazu Furutani, Fenyu Ren, Yuhki Yamaguchi, Kohki Yutoku, Satoyoshi Yamashita, Michiari Okuda, Misako Okita, Kiwamu Okita

Journal:

Journal of Gastroenterology and Hepatology

Year:

2006

Language:

english

File:

PDF, 316 KB

english, 2006

33

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

Hong, Hyenjong, Takahashi, Kazutoshi, Ichisaka, Tomoko, Aoi, Takashi, Kanagawa, Osami, Nakagawa, Masato, Okita, Keisuke, Yamanaka, Shinya

Journal:

Year:

2009

Language:

english

File:

PDF, 526 KB

english, 2009

34

Variation in the safety of induced pluripotent stem cell lines

Miura, Kyoko, Okada, Yohei, Aoi, Takashi, Okada, Aki, Takahashi, Kazutoshi, Okita, Keisuke, Nakagawa, Masato, Koyanagi, Michiyo, Tanabe, Koji, Ohnuki, Mari

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 468 KB

english, 2009

35

Generation of mouse-induced pluripotent stem cells with plasmid vectors

Okita, Keisuke, Hong, Hyenjong, Takahashi, Kazutoshi, Yamanaka, Shinya

Journal:

Nature Protocols

Year:

2010

Language:

english

File:

PDF, 910 KB

english, 2010

36

Genome-wide DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) residing in mouse pluripotent stem cells

Shinya Sato, Shintaro Yagi, Yoshikazu Arai, Keiji Hirabayashi, Naoko Hattori, Misa Iwatani, Keisuke Okita, Jun Ohgane, Satoshi Tanaka, Teruhiko Wakayama, Shinya Yamanaka, Kunio Shiota

Journal:

Year:

2010

Language:

english

File:

PDF, 1.33 MB

english, 2010

37

Expression of Type I Interferon Receptor in Liver and Peripheral Blood Mononuclear Cells in Chronic Hepatitis C Patients

Yuhki Yamaguchi, Keisuke Hino, Daisuke Fujiwara, Fenyu Ren, Yoshiharu Katoh, Yasuhiro Satoh, Kiwamu Okita

Journal:

Digestive Diseases and Sciences

Year:

2002

Language:

english

File:

PDF, 364 KB

english, 2002

38

Correlation Between Relative Number of Circulating Low-Density Hepatitis C Virus Particles and Disease Activity in Patients with Chronic Hepatitis C

Keisuke Hino, Kaori Fujii, Masaaki Korenaga, Chisa Murakami, Muneko Okazaki, Michiari Okuda, Kiwamu Okita

Journal:

Digestive Diseases and Sciences

Year:

1997

Language:

english

File:

PDF, 162 KB

english, 1997

39

Epstein-barr virus association is rare in esophageal squamous cell carcinoma

Hideo Yanai, Atsuyoshi Hirano, Keisuke Matsusaki, Toyokazu Kawano, Osamu Miura, Tomoharu Yoshida, Kiwamu Okita, Norio Shimizu

Journal:

Journal of Gastrointestinal Cancer

Year:

2003

Language:

english

File:

PDF, 104 KB

english, 2003

40

Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan

Etsuro Orito, Takafumi Ichida, Hiroshi Sakugawa, Michio Sata, Norio Horiike, Keisuke Hino, Kiwamu Okita, Takeshi Okanoue, Shiro Iino, Eiji Tanaka, Kazuyuki Suzuki, Hisayoshi Watanabe, Shuhei Hige, Mas

Journal:

Year:

2001

Language:

english

File:

PDF, 689 KB

english, 2001

41

Methods for iPS cell generation for basic research and clinical applications

Yuji Mochiduki, Dr. Keisuke Okita

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 369 KB

english, 2012

42

Serial assay of hepatitis C virus RNA in serum for predicting response to interferon-α therapy

Keisuke Hino, Michiari Okuda, Tomomi Konishi, Hiroaki Ishiko, Kiwamu Okita

Journal:

Digestive Diseases and Sciences

Year:

1995

Language:

english

File:

PDF, 683 KB

english, 1995

43

Glycine-to-arginine substitution at codon 145 of HBsAg in two infants Born to hepatitis B e antigen-positive carrier

Keisuke Hino, Michiari Okuda, Osamu Hashimoto, Hiroaki Ishiko, Muneko Okazaki, Kaori Fujii, Hiroshi Hanada, Kiwamu Okita

Journal:

Digestive Diseases and Sciences

Year:

1995

Language:

english

File:

PDF, 450 KB

english, 1995

44

Hepatic fas antigen expression before and after interferon therapy in patients with chronic hepatitis C

Muneko Okazaki, Keisuke Hino, Kaori Fujii, Nobuyuki Kobayashi, Kiwamu Okita

Journal:

Digestive Diseases and Sciences

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

45

Hepatocellular Carcinoma with a Sarcomatous Appearance: Report of a Case

Yoshihiko Tsuji, Kenji Okada, Masato Fukuoka, Yoshihisa Watanabe, Keiji Ataka, Rieko Minami, Keisuke Hanioka, Shiro Tachibana, Hiroshi Saito, Akinori Sasada, Yutaka Okita

Journal:

Year:

2001

Language:

english

File:

PDF, 690 KB

english, 2001

46

Immunohistochemical study of Fas antigen in liver of patients with chronic hepatitis and autoimmune liver disease

Muneko Okazaki, Keisuke Hino, Kaori Fujii, Hiroshi Hanada, Yoshinobu Nakanishi, Susumu Kanazawa, Nobuyuki Kobayashi, Kiwamu Okita

Journal:

International Hepatology Communications

Year:

1995

Language:

english

File:

PDF, 732 KB

english, 1995

47

Reverse diastolic flow in the common carotid artery in severe aortic regurgitation, causing brain ischemia

Naoto Morimoto, Keisuke Morimoto, Yoshihisa Morimoto, Toshihito Sakamoto, Masamichi Matsumori, Kenji Okada, Yutaka Okita

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2008

Language:

english

File:

PDF, 309 KB

english, 2008

48

Palliative bidirectional Glenn anastomosis for unresectable metastasis in the right ventricle from renal cell carcinoma 16 years after nephrectomy

Naoto Morimoto, Keisuke Morimoto, Yoshihisa Morimoto, Toshihito Sakamoto, Akiko Tanaka, Masamichi Matsumori, Kenji Okada, Yutaka Okita

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2009

Language:

english

File:

PDF, 203 KB

english, 2009

49

Vitamin E and C supplementation prevents decrease of eicosapentaenoic acid in mononuclear cells in chronic hepatitis C patients during combination therapy of interferon α-2b and ribavirin

Yasuko Murakami, Ayako Nagai, Takayo Kawakami, Keisuke Hino, Akira Kitase, Yuh-ichi Hara, Michiari Okuda, Kiwamu Okita, Misako Okita

Journal:

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

50

Induction of pluripotency by defined factors

Keisuke Okita, Shinya Yamanaka

Journal:

Experimental Cell Research

Year:

2010

Language:

english

File:

PDF, 236 KB

english, 2010